A simple, focused Skript addon that will give you easier world guard elements into Skript.

Dependencies:
.- World Guard
.- World Edit
.-Skript

Effects:

.- Define Region:
Syntax:
define region %string% from %location% to %location% in %world%
Example:
set {_loc1} to location at 0, 40, 0
set {_loc2} to location at 16, 40, 16
define region "spawn" from {_loc1} to {_loc2} in player's world